What is bioavailability?  

What is bioavailability and what does it mean for you?   In this post we will briefly review bioavailability and how it pertains to your options when buying CBD products.

Perhaps you have heard of bioavailability from a physician, pharmacist or supplement company.  Bioavailability specifies the proportion of a substance entering the body that is actually absorbed into the circulatory system. In simpler terms,  bioavailability is how quickly, how much and how effectively your body absorbs what you put into it such as, a pharmaceutical and nutrients from foods or supplements.

Bioavailability is crucial from a nutritional standpoint because we depend on many essential vitamins and minerals to stay healthy and to fight disease. It is common knowledge that eating fruits and vegetables will assist in your health and wellness. There are a few key factors that directly effect bioavailability such as, age, genetics, current health, how food is prepared and the food source to name a few. Just because we ingest various nutrients, does not mean that they are actually making it all the way to our bloodstream and ultimately, to our cells.

Bioavailability and CBD

Understanding bioavailability and nutrition is very important and a full post for another day. What about how bioavailability pertains to CBD?  CBD can be administered in so many different ways. How do we know what is the most bioavailable way to consume our CBD? How will we get the most out of its incredible health benefits?  These are some of the different methods of administering CBD and how each affects its bioavailability.


CBD tincture, oral spray, and lozenges are all considered sublingual.  When a substance is taken orally, especially under the tongue, it goes directly into the bloodstream, making it extremely bioavailable. This typically has a much faster reaction time and impacts the body more rapidly.  Additionally, studies have shown that holding the CBD under your tongue for a minute allows most of the active ingredients in the CBD to be absorbed through the capillaries. By allowing CBD to bypass the digestive tract and the liver, the sublingual administration most likely increases the compounds effectiveness.   


Edibles are a very popular way to ingest your CBD.  There are a wide variety of mediums from which to choose.  These include gummies, chocolate, hard candies, carbonated CBD beverages and more.  Because most edibles are small, they are easy to carry around and easily accessed when needed.  Another benefit about edibles is that the dosage is pre measured so you’ll always know the exact amount of mg’s you’re consuming at one time.  Edibles take a little longer to be reach the bloodstream because they have to go through the digestive system first. If you’re looking for something a little more bioavailable,  you might want to try another manner of ingestion, like a tincture.


Topical administration of CBD is also a very acceptable way to use hemp products.  There are oils, lotions, creams, lip balms, bath balms and numerous other applications that are a more than adequate means to receive the health benefits you’re looking for.  The skin is your biggest organ so it seems appropriate to utilize it as a means to internalize CBD. Human skin is extremely permeable, allowing the CBD to be more bioavailable than some other options. You will need to apply very generously to affect targeted area.


Many prefer the simplicity of taking a pill or capsule as opposed to some of the other options.  Capsules are discreet and the dosage is typically very accurate.  This is a fine way to consume CBD but the downfall is that it takes longer for the supplement to take effect.  The bioavailability is less, as well, because the pill moves through all of the body’s filtration systems.

What is best for you?

When choosing a CBD product, it is important to understand the bioavailability of any particular product. More importantly are the quality of the CBD oil, the company from which you buy, and the source of the hemp.  These factors will reassure you that you are receiving exactly what is advertised on the package.

There is no right or wrong way to take  CBD.  It is a personal preference and experimentation is key. The goal is to maximize the bioavailability of any substance taken to treat health issues or enhance nutrition.  CBD is no different and the importance of researching and speaking with a CBD educated practitioner, can be a great way to figure out what’s best for you.


  1. https://www.cannahealth.org/cbd-bioavailability-whats-the-best-way-to-absorb-cbd/
  2. https://cbdsky.com/bioavailability-of-cbd-why-it-matters/
  3. https://www.cannahealth.org/cbd-bioavailability-whats-the-best-way-to-absorb-cbd/